One step aqueous synthesis of unprotected glycosyl C-sulfonates
A one-step reaction for the production of unprotected glycosyl C-sulfonates directly from reducing sugars in aqueous solution has been developed, avoiding the use of any protecting groups. The reaction is equally applicable to disaccharides. The structure of the β-gluco C-sulfonate was confirmed by X-ray crystallography. Investigations showed that it did not inhibit almond β-glucosidase at a concentration of 100 μM.
Authors
- Frank N. Wilson
- Antony J. Fairbanks (ORCID: https://orcid.org/0000-0002-9975-3269)
- Govind Singh (ORCID: https://orcid.org/0000-0001-5692-434X)
- Nathan H. Reid
Institutions
- University of Canterbury (NZ)
- Sikkim University (IN)
- MacDiarmid Institute for Advanced Materials and Nanotechnology (NZ)
Publication Details
- Journal
- Carbohydrate Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.carres.2025.109411
- Citations
- 2
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Council of Scientific and Industrial Research, India