Antifungal effects of natural extracts on Candida albicans
Fungal infections caused by <i>Candida albicans</i> present significant challenges in clinical settings owing to rising resistance to conventional antifungal treatments. Natural products derived from medicinal plants, including tulsi (<i>Ocimum sanctum</i>), garlic (<i>Allium sativum</i>), cinnamon (<i>Cinnamomum verum</i>) and lemongrass (<i>Cymbopogon citratus</i>), are increasingly recognized for their potential antimicrobial properties and as alternative sources of antifungal therapies. This study evaluated the antifungal efficacy of Tulsi, Garlic, Cinnamon and Lemongrass extracts against <i>Candida albicans</i> using disk diffusion and broth microdilution methods. Natural extracts from Tulsi, Garlic, Cinnamon and Lemongrass demonstrated varying degrees of antifungal activity against <i>Candida albicans</i>. Tulsi emerged as the most effective, followed by garlic and cinnamon, whereas lemongrass showed comparatively lower efficacy. These findings underscore Tulsi's potential as a potent natural antifungal agent and warrant further exploration of its therapeutic applications in fungal infections.
Authors
- Aditya Rawal (ORCID: https://orcid.org/0000-0002-5396-1265)
- Rahul Shrivastava (ORCID: https://orcid.org/0000-0002-8544-5046)
- Naina Pattnaik
- Megha Goyal (ORCID: https://orcid.org/0000-0002-7182-669X)
- Arpita Srivastava (ORCID: https://orcid.org/0000-0002-6081-2444)
- Angel Aghera
Institutions
- ITM University (IN)
- Government Dental College and Hospital (IN)
- MNR Dental College and Hospital (IN)
- People’s University (IN)
- KIIT University (IN)
Publication Details
- Journal
- Bioinformation
- Published
- 2024-09-30
- DOI
- https://doi.org/10.6026/9732063002001142
- Citations
- 1
- Primary Topic
- Essential Oils and Antimicrobial Activity
- Type
- article
- Field-Weighted Citation Impact
- 0.35