Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation
In conclusion, this study revealed Puerarin may regulate the ferroptosis process by inhibiting the JAK2/STAT3 pathway for the treatment of DLI.
Authors
- Xiaoxu Fan (ORCID: https://orcid.org/0000-0002-6487-3797)
- Wei Lan (ORCID: https://orcid.org/0009-0006-7937-4743)
- Shuangqiao Liu (ORCID: https://orcid.org/0000-0002-9885-9352)
- Yiwei Shen
- Jianhua Ma (ORCID: https://orcid.org/0000-0001-9383-2559)
- Jingxia Wang (ORCID: https://orcid.org/0000-0001-9852-4811)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-9368-6149)
- Jing Yu (ORCID: https://orcid.org/0009-0005-8558-9217)
- Yingtong Feng (ORCID: https://orcid.org/0009-0000-3370-5996)
Institutions
- Xinjiang Medical University (CN)
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dddt.s487496
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 6.07