https://www.ejmr.org/articals/pdf/1736150955_825b76944d660f3e5c96.pdf

Background: ABO blood type markers are present on the cell membranes of epithelial and endothelial layers, as well as on nerve cells. Numerous studies have highlighted a correlation between the risk of developing certain cancer types and ABO blood group antigens. Risk factors like smoking, alcohol consumption, diet, and radiation exposure play a significant role. Neuroma, a benign tumor of nerve tissue, is often associated with pain or various other specific symptoms. It typically develops from non-neuronal nervous tissue following amputation or trauma, though it can also be a true neoplasm. Approximately 6% of individuals may develop a neuroma.Aim and Objective: The main goal of this research was to analyze existing studies and Exploring the correlation between blood types and brain tumors. Material and Methods: Original, relevant, and up-to-date articles in the same field were reviewed to provide a comprehensive analysis of this topic. In doing so, critical discussions were included, offering not just a descriptive overview but also a thorough presentation of contradictory viewpoints in a clear manner. Research queries were carried out by matching terms associated with blood groups and tumors of the nervous system. Result: People with blood group B showed an increased incidence of cavernomas, gliomas, meningiomas, pituitary adenomas, schwannomas, and other tumors, with a declining trend in prevalence across blood type O, A, and AB. The link between blood type O and neuroma was the sole correlation to reach statistical significance. The likelihood of glioma was greater among individuals with AB blood type regarding other ABO blood types. Those with blood type A were more susceptible to developing glioblastoma compared to individuals with blood type O. Conclusion: It was determined that no meaningful correlation existed between blood group antigens and brain neoplasms in the general population. While neuroma showed a distinct association with blood group O, its occurrence in the population is relatively rare.