Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum
Aside from elucidating the underlying mechanism whereby gut microbiota dysbiosis is linked to AD, our findings may contribute to groundwork for future interventions targeting the microbiota-metabolites-brain-cognition pathways as a therapeutic strategy in the AD continuum.
Authors
- Han Zhao (ORCID: https://orcid.org/0000-0002-3528-9938)
- Yongqiang Yu (ORCID: https://orcid.org/0000-0001-8977-2215)
- Zhongwu Sun (ORCID: https://orcid.org/0000-0002-7230-9328)
- Jiajia Zhu (ORCID: https://orcid.org/0000-0001-7343-6241)
- Wenming Zhao (ORCID: https://orcid.org/0000-0002-4396-8287)
- Xia Zhou
- Yu Song
Institutions
- Anhui Medical University (CN)
- Anhui Provincial Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- China Construction Bank (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1186/s13195-025-01683-0
- Citations
- 36
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 29.02
Funders
- National Natural Science Foundation of China
- Anhui Medical University
- Natural Science Foundation of Anhui Province