Concomitant Use of Etrasimod With Opioids or Antidepressants in Patients With Ulcerative Colitis—A Safety Analysis
The incidence of AEs was low and comparable in patients receiving etrasimod with or without concomitant opioids or antidepressants. This analysis further supports the low likelihood of clinically relevant drug-drug interactions between etrasimod and medications commonly prescribed to patients with UC, such as opioids or antidepressants. (ClinicalTrials.gov: NCT03945188; NCT03996369).
Authors
- Krisztina Lazin
- Michael J. Keating (ORCID: https://orcid.org/0000-0002-9121-6450)
- Anita Afzali (ORCID: https://orcid.org/0000-0002-4397-9576)
- Andrés Yarur (ORCID: https://orcid.org/0000-0003-2293-5555)
- Laurent Peyrin‐Biroulet (ORCID: https://orcid.org/0000-0003-2536-6618)
- Siew C. Ng (ORCID: https://orcid.org/0000-0002-6850-4454)
- Yamile Zabana (ORCID: https://orcid.org/0000-0003-4023-8868)
- Diogo Branquinho (ORCID: https://orcid.org/0000-0001-8519-6409)
- Miguel D. Regueiro (ORCID: https://orcid.org/0000-0002-7681-8111)
- Eustratios Bananis
- Abhishek Bhattacharjee (ORCID: https://orcid.org/0000-0002-1053-8408)
- Aoibhinn McDonnell (ORCID: https://orcid.org/0000-0002-2229-0382)
- Sujatha Menon
Institutions
- Cedars-Sinai Medical Center (US)
- Cleveland Clinic (US)
- Inserm (FR)
- Chinese University of Hong Kong (HK)
- Pfizer (United States) (US)
- Pfizer (United Kingdom) (GB)
- Pfizer (Switzerland) (CH)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Mútua Terrassa (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Pfizer (India) (IN)
- Nutrition-Génétique et Exposition aux Risques Environnementaux (FR)
- Université de Lorraine (FR)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- United European Gastroenterology Journal
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/ueg2.12745
- Citations
- 1
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Pfizer