Pilocytic astrocytoma: A rare case report

Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its' slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes.

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Publication Details

Journal
Radiology Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1016/j.radcr.2025.01.025
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Pilocytic astrocytoma: A rare case report

Harry Galuh Nugraha, Mirna Sobana, Hermin Aminah Usman, Elsa Yoasta
Radiology Case Reports
Glioma Diagnosis and Treatment
article

Pilocytic astrocytoma: A rare case report

Harry Galuh Nugraha, Mirna Sobana, Hermin Aminah Usman, Elsa Yoasta
article en

Abstract

Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its' slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes.

Radiology Case ReportsVol. 20(4)
Dr. Hasan Sadikin General Hospital (ID)
Universitas Padjadjaran
Zero hunger
Openalex Percentile: Top 97%
Glioma Diagnosis and Treatment
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