SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma cells
Our data deciphered the mechanism of ETV1-mediated M2 macrophage infiltration in the TME of ESCC, which has important implications for the development of novel prognostic and therapeutic targets to optimize current therapies against ESCC.
Authors
- Xiaoqi Guo
- Tianci Han
- Liang Zhang (ORCID: https://orcid.org/0000-0002-5661-3557)
- Tong Wei (ORCID: https://orcid.org/0009-0003-4094-3468)
- Junwei Xie (ORCID: https://orcid.org/0009-0004-2906-3838)
Institutions
- Dalian University of Technology (CN)
- Liaoning University of Traditional Chinese Medicine (CN)
- Liaoning Cancer Hospital & Institute (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s00262-024-03914-z
- Citations
- 7
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 5.58
Funders
- Dalian University of Technology