The value of serum tumor-associated autoantibodies in screening and diagnosis of gastric cancer
The determination of serum autoantibody panel has clinical value in screening and prediction of gastric cancer, and can be used as an auxiliary index in clinical diagnosis. The combination of 7-TAAs and Helicobacter pylori can effectively improve the screening specificity and positive predictive value. The detection results of different proteins were related to the stage of disease, the degree of tumor differentiation and the depth of invasion.
Authors
- Hua-xing Wei
- Yanchun Wang (ORCID: https://orcid.org/0000-0002-0203-7312)
- Congying Xie (ORCID: https://orcid.org/0000-0002-1693-9034)
- Hao Wang (ORCID: https://orcid.org/0000-0003-4909-8937)
- Wenqian Dong (ORCID: https://orcid.org/0000-0002-0692-9676)
- Kangjia Xiao
- Renquan Lu (ORCID: https://orcid.org/0000-0003-3291-5742)
- Yanping Hu (ORCID: https://orcid.org/0000-0001-7128-2648)
- Qingtian Li (ORCID: https://orcid.org/0000-0003-1170-0806)
- Meihua Kang
- Baolong Wang (ORCID: https://orcid.org/0000-0003-0163-7575)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-5914-8024)
Institutions
- University of Science and Technology of China (CN)
- Ruijin Hospital (CN)
- Shanghai International Medical Center (CN)
- Fudan University Shanghai Cancer Center (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.cca.2025.120167
- Citations
- 1
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Natural Science Foundation of China