A rare finding of testicular epidermoid keratinized cyst in a prepubertal boy: case report and management standardization

Testicular epidermoid cysts (TECs) are rare, benign lesions that can also mimic malignant testicular masses. Accurate preoperative diagnosis is essential for proper management. A 13-year-old male presented with a painless solid mass in the left testicle. Serum tumor markers were normal. Ultrasound, CEUS and MRI findings were consistent with TEC. Surgical enucleation of the mass was performed, after ruling out malignancy through intraoperative frozen section examination. Histopathology confirmed diagnosis of keratin-filled epidermoid cyst. At 3-month follow-up, the patient is well-being and scrotal US is normal. This case highlights the importance of considering epidermoid cysts in the differential diagnosis of testicular masses in young males. Ultrasound is the first-line imaging modality in the assessment of any testicular masses. Other imaging modalities such as CEUS, elastography and MRI can be helpful to distinguish between benign and malignant lesions. Testis-sparing surgery can be safely performed, after ruling out malignancy through intraoperative frozen-section analysis.

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Publication Details

Journal
Journal of Ultrasound
Published
2025-02-01
DOI
https://doi.org/10.1007/s40477-025-00992-2
Citations
2
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
4.01

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article

A rare finding of testicular epidermoid keratinized cyst in a prepubertal boy: case report and management standardization

Claudia Di Mento, Annalisa Chiodi, Pasquale Somma, Maria Escolino et al.
2 citations
Journal of Ultrasound
Testicular diseases and treatments
4.01
article

A rare finding of testicular epidermoid keratinized cyst in a prepubertal boy: case report and management standardization

Claudia Di Mento, Annalisa Chiodi, Pasquale Somma, Maria Escolino, Francesca Carraturo, Ciro Esposito, Giorgia Esposito, Mauro Porcaro, Valerio Mazzone
article en
2 citations

Abstract

Testicular epidermoid cysts (TECs) are rare, benign lesions that can also mimic malignant testicular masses. Accurate preoperative diagnosis is essential for proper management. A 13-year-old male presented with a painless solid mass in the left testicle. Serum tumor markers were normal. Ultrasound, CEUS and MRI findings were consistent with TEC. Surgical enucleation of the mass was performed, after ruling out malignancy through intraoperative frozen section examination. Histopathology confirmed diagnosis of keratin-filled epidermoid cyst. At 3-month follow-up, the patient is well-being and scrotal US is normal. This case highlights the importance of considering epidermoid cysts in the differential diagnosis of testicular masses in young males. Ultrasound is the first-line imaging modality in the assessment of any testicular masses. Other imaging modalities such as CEUS, elastography and MRI can be helpful to distinguish between benign and malignant lesions. Testis-sparing surgery can be safely performed, after ruling out malignancy through intraoperative frozen-section analysis.

Journal of Ultrasound
Federico II University Hospital (IT)
Università degli Studi di Napoli Federico II
Good health and well-being
Openalex Percentile: Top 9%
Testicular diseases and treatments
4.01
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