Neoadjuvant Chemoradiotherapy Using Moderately Hypofractionated Intensity-Modulated Radiotherapy Versus Upfront Surgery for Resectable Pancreatic Cancer: A Retrospective Cohort Study
NAC-IMRT may offer superior survival outcomes and manageable toxicity in R-PDAC patients compared with upfront surgery. This study supports the efficacy and safety of NAC-IMRT and recommends its consideration in R-PDAC treatment protocols.
Authors
- Kei Yamane (ORCID: https://orcid.org/0000-0002-9543-0841)
- Satoshi Ishida (ORCID: https://orcid.org/0000-0001-5905-8168)
- Satoshi Ogiso (ORCID: https://orcid.org/0000-0002-9577-330X)
- Takahiro Iwai
- Kazuyuki Nagai (ORCID: https://orcid.org/0000-0003-2180-2056)
- Michio Yoshimura (ORCID: https://orcid.org/0000-0001-6665-2245)
- Takayuki Anazawa (ORCID: https://orcid.org/0000-0002-7625-5750)
- Yu Hidaka (ORCID: https://orcid.org/0000-0003-3637-4429)
- Etsuro Hatano (ORCID: https://orcid.org/0000-0003-3407-1918)
- Yosuke Kasai (ORCID: https://orcid.org/0000-0003-2815-6309)
- Akihisa Fukuda (ORCID: https://orcid.org/0000-0002-1940-596X)
- Koki Kurahashi
- Aya Izuwa (ORCID: https://orcid.org/0009-0004-9165-1438)
- Toshihiko Masui (ORCID: https://orcid.org/0000-0002-4001-4824)
- Yumiko Ibi
- Hiroyoshi Isoda (ORCID: https://orcid.org/0000-0002-1789-7390)
- Junichi Matsubara (ORCID: https://orcid.org/0000-0003-0116-5133)
Institutions
- Kyoto University (JP)
- Kurashiki Central Hospital (JP)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1245/s10434-025-16956-z
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Japan Society for the Promotion of Science