Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study
In conclusion, FH was causally positive-associated with the increased risk of intestinal vascular diseases, revealing a potential unfortunate outcome for FH. Therefore, patients with FH should pay closely attention to the risk of intestinal vascular diseases. Our study may provide evidence for new diagnostic and therapeutic strategies in clinical practices.
Authors
- Gang Wei (ORCID: https://orcid.org/0000-0002-8051-5260)
- Feng‐Jie Shen (ORCID: https://orcid.org/0000-0003-1005-1330)
- Cheng Zhang (ORCID: https://orcid.org/0009-0008-2698-5019)
- Hongying Guo (ORCID: https://orcid.org/0000-0002-9282-9638)
- Lin Liu (ORCID: https://orcid.org/0000-0002-1934-1847)
Institutions
- Beijing Tongren Hospital (CN)
- Shanghai Jiao Tong University (CN)
- Capital Medical University (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Metabolism Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.metop.2025.100352
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Guizhou Medical University
- Key Technologies Research and Development Program
- National Key Research and Development Program of China