Insights into psychosis risk: Unveiling impaired reinforcement learning through a behavioral and functional near-infrared spectroscopy-based optical neuroimaging study
Our findings indicate impaired reward feedback processing in CHR-P subjects, suggesting reduced sensitivity to reward. This is reflected in decreased task-induced response in cerebrovascular [tHb], indicating lower task-relevant prefrontal activities compared to HC subjects. These findings suggest that impaired processing of reward feedback may contribute to reward learning deficits and inflexible cognition in CHR-P subjects.
Authors
- Jochen Kindler (ORCID: https://orcid.org/0000-0002-9034-2770)
- Chantal Michel
- Michael Kaess (ORCID: https://orcid.org/0000-0003-0031-7764)
- Felix Scholkmann (ORCID: https://orcid.org/0000-0002-1748-4852)
- Miriam Stüble
- Arndt-Lukas Klaassen
Institutions
- University of Bern (CH)
- Bern University of Applied Sciences (CH)
- University of Zurich (CH)
- Heidelberg University (DE)
- University Hospital of Bern (CH)
- University Hospital Heidelberg (DE)
- University Hospital of Zurich (CH)
- Psychiatry Baselland (CH)
Publication Details
- Journal
- Journal of Psychiatric Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.jpsychires.2025.01.051
- Primary Topic
- Mental Health Research Topics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Bern