Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial
Differing berry (poly)phenol content and bioaccessibility only minimally affect bioavailability following consumption of blueberries relative to a blueberry-rich protein bar, suggesting (poly)phenol-dense foods, such as bars and snacks, could provide similar health benefits as raw fruits. Further studies using other crops are required to assess if these findings are translatable. This trial was registered at clinicaltrials.gov as NCT04175106.
Authors
- Joscelin T. Diaz (ORCID: https://orcid.org/0000-0001-6415-6176)
- Mário G. Ferruzzi (ORCID: https://orcid.org/0000-0003-1384-2672)
- Massimo Iorizzo (ORCID: https://orcid.org/0000-0002-0032-8247)
- Harry Edmar Schulz (ORCID: https://orcid.org/0000-0002-2827-0112)
- Monique Carvalho de Santana (ORCID: https://orcid.org/0000-0002-0201-7725)
- Colin D. Kay (ORCID: https://orcid.org/0000-0001-7290-4496)
- Mary Ann Lila (ORCID: https://orcid.org/0000-0002-4928-3836)
- Preeti Chandra (ORCID: https://orcid.org/0000-0002-1794-103X)
- Jessica Everhart
- Atul Rathore (ORCID: https://orcid.org/0000-0003-2191-9465)
- Cheryl D Granillo
Institutions
- North Carolina State University (US)
- North Carolina Agricultural and Technical State University (US)
- Arkansas Children's Nutrition Center (US)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- American Journal of Clinical Nutrition
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.ajcnut.2025.01.028
- Citations
- 2
- Primary Topic
- Phytochemicals and Antioxidant Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Foundation for Food and Agriculture Research