Long-term Response to SARS-CoV-2 mRNA Vaccine in Adolescents

The BNT162b2 vaccine induced robust initial immune responses in adolescents; however, the immunity waned over time. Booster doses are essential for sustained protection, especially against emerging variants. Breakthrough infections further enhance antibody responses, highlighting the benefits of hybrid immunity. The safety profile is generally favorable; however, ongoing monitoring is warranted.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-01-28
DOI
https://doi.org/10.1097/inf.0000000000004709
Citations
1
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
1.40
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Long-term Response to SARS-CoV-2 mRNA Vaccine in Adolescents

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The Pediatric Infectious Disease Journal
SARS-CoV-2 and COVID-19 Research
1.40
article

Long-term Response to SARS-CoV-2 mRNA Vaccine in Adolescents

Yoo Jin Na, Seokhwan Hyeon, Eun Bee Choi, Seung Ha Song, Ki Wook Yun, Kwangwook Kim, Heeji Lim, Mi Seon Han, Yun Kyung Kim, Young June Choe, Ye Kyung Kim, Bin Ahn, Hye‐Kyung Cho, Yoo-kyoung Lee, Eun Hwa Choi, Soyeon Ahn, Sung‐Hwan Choi, Byung Chul Kim, Yoonsun Yoon, Su-Jin Choi, Soyeon Lee
article en
1 citations

Abstract

The BNT162b2 vaccine induced robust initial immune responses in adolescents; however, the immunity waned over time. Booster doses are essential for sustained protection, especially against emerging variants. Breakthrough infections further enhance antibody responses, highlighting the benefits of hybrid immunity. The safety profile is generally favorable; however, ongoing monitoring is warranted.

The Pediatric Infectious Disease JournalVol. 44(6)
Gachon University (KR), Seoul National University (KR), Korea University (KR), Korea University Medical Center (KR), Seoul Metropolitan Government (KR), Seoul National University Bundang Hospital (KR), Ansan University (KR), Korea National Institute of Health (KR), SNUH SMG-SNU Boramae Medical Center (KR), Seoul National University Children's Hospital (KR)
Good health and well-being
Openalex Percentile: Top 25%
SARS-CoV-2 and COVID-19 Research
1.40
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