Meningeal large B-cell lymphoma: Beware of the meningioma trap! A case report with review of the literature

Primary meningeal lymphoma of the central nervous system is extremely rare. Over the past decade, a number of these tumors have been reported to resemble meningioma clinically, intraoperatively and radiologically. We report the clinical, radiological, histopathological and evolutive features of a primary parieto-occipital meningeal lymphoma in a 27-year-old man, which clinically and radiologically resembled an aggressive high-grade meningioma. The patient was initially treated by surgery and then referred to hematology for possible further chemo-radiotherapy. The unfavorable evolution of the patient was due to the neurological sequelae of the surgical resection despite the regression of the tumor process objectified by follow-up imaging. Therefore, primary meningeal lymphoma of the central nervous system should be included in the differential diagnosis of meningioma and warrants anatomopathological and immunohistochemical examination of any surgical specimen and follow-up imaging.