Tick bite fever in South Africa (A Rickettsial Disease)

Tick bite fever has been a constant scenario in South Africa. Only recently has it been established that there are two aetiological agents. These two agents have different epidemiologies and clinical presentations. They are Ricketsia conorii and Rickettsia Africa. Rickettsia Africa is the milder form of the disease. Rickettsia conorii can be fatal! The treatment of choice is doxycycline or tetracycline. Macrolides and quinolones may be of value.