Physical Exercise Improve Pancreatic Beta Cell Mass and Function: Systematic Review

This study aims to analyze the effects of exercise on the mass and function of pancreatic beta cells. This type of systematic review research uses searches from journal databases such as Science Direct, Pubmed, and Web of Science. The inclusion criteria for this study are studies that discuss the hormone insulin, pancreatic beta cells, diabetes mellitus, and physical activity published in the last five years (2018-2023). The exclusion criteria for this research are publications published in non-reputable journals or not indexed by Scopus and Web of Science.Article titles, abstracts, and complete texts were vetted, confirmed, and entered into Mendeley software. 10 articles that met the inclusion criteria were selected and analyzed for this systematic review. This systematic review study's findings indicate that enhancing the mass and functionality of pancreatic beta cells led to by physical exercise can increase the sensitivity of the action of the hormone insulin. This has an influence on the maintenance of the pancreas organ, especially beta cells which work to maintain blood glucose balance in the body by secreting the hormone insulin. We recommend that physical exercise be a preventive effort for each individual to maintain the body to care for one of the organs that is very important in blood glucose balance, namely the pancreas by increasing the size and functionality of beta cells in the pancreas. And maintain general body health.