Buckwheat Protein-Induced Enterocolitis Syndrome: A Series of Clinical Cases

Introduction. Case reports of Food Protein-Induced Enterocolitis Syndrome (FPIES) associated with buckwheat consumption are quite rare. However, over the course of 3 years at the Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of Russia, we observed 3 patients who can be considered cases of this rare pathology. Presentation of the clinical case. The article briefly describes the cases of Food Protein-Induced Enterocolitis Syndrome, associated with consumption of buckwheat porridge, in three patients — 11 months, 7 months, and 7.5 years old. All cases featured an acute form of FPIES of varying severity, with a typical form (absence of specific IgE to buckwheat proteins). The elimination diet excluding the trigger protein was effective in all cases. Two patients were able to reintroduce buckwheat porridge into their diet after 12 months. The 7.5-year-old girl was recommended to continue with the elimination diet for 18 months. Conclusion. Although buckwheat porridge is generally considered a “hypoallergenic” complementary food, it is important to be aware of the possibility of atypical reactions such as FPIES.