Comparative effectiveness of intraarticular injection of PRP and implantation of heparin-conjugated fibrin hydrogel in osteoarthrosis of the knee joint

Aim of the study . The article is devoted to the current trend of modern orthopedics – the surgical treatment of local full-thickness defects in the hyaline cartilage of the knee joint. This pathology is diagnosed in 5-10% of patients with diseases and injuries of the knee joint. Materials and methods . The authors of the article presented one of the most modern and available technologies for the restoration of cartilage defects – the implantation of Heparin-Conjugated Fibrin Hydrogel. This operation technique was used in 38 patients. The article presents the indications and technique of surgery, criteria for evaluating treatment outcomes. Results and discussion . Treatment outcomes in terms of up to 2 years were studied in 38 patients. Good treatment results were observed in 33 patients. In all cases, high-quality and regeneration of the cartilaginous surface of the femoral condyles was achieved. Conclusion . Analysis of the outcomes of treatment of patients after implantation implantation of Heparin- Conjugated Fibrin Hydrogel allows the authors of the article to recommend this technique for widespread use in clinical practice.

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Publication Details

Journal
Medicine and ecology
Published
2025-01-22
DOI
https://doi.org/10.59598/me-2305-6045-2024-113-4-91-102
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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article

Comparative effectiveness of intraarticular injection of PRP and implantation of heparin-conjugated fibrin hydrogel in osteoarthrosis of the knee joint

Mukhtar Abilmazhinov, Arman Batpen, Tusipkhan Toktarov, Dina Saginova et al.
Medicine and ecology
Osteoarthritis Treatment and Mechanisms
article

Comparative effectiveness of intraarticular injection of PRP and implantation of heparin-conjugated fibrin hydrogel in osteoarthrosis of the knee joint

Mukhtar Abilmazhinov, Arman Batpen, Tusipkhan Toktarov, Dina Saginova, Bagdat Balbossynov, Vyacheslav B. Ogay, Yerik Raimagambetov, Kaissar Karkyn
article en

Abstract

Aim of the study . The article is devoted to the current trend of modern orthopedics – the surgical treatment of local full-thickness defects in the hyaline cartilage of the knee joint. This pathology is diagnosed in 5-10% of patients with diseases and injuries of the knee joint. Materials and methods . The authors of the article presented one of the most modern and available technologies for the restoration of cartilage defects – the implantation of Heparin-Conjugated Fibrin Hydrogel. This operation technique was used in 38 patients. The article presents the indications and technique of surgery, criteria for evaluating treatment outcomes. Results and discussion . Treatment outcomes in terms of up to 2 years were studied in 38 patients. Good treatment results were observed in 33 patients. In all cases, high-quality and regeneration of the cartilaginous surface of the femoral condyles was achieved. Conclusion . Analysis of the outcomes of treatment of patients after implantation implantation of Heparin- Conjugated Fibrin Hydrogel allows the authors of the article to recommend this technique for widespread use in clinical practice.

Medicine and ecology(4)
Central Scientific Research Institute of Traumatology and Orthopedics (RU), Astana Medical University (KZ), Alikhan Bokeikhan University
Openalex Percentile: Top 97%
Osteoarthritis Treatment and Mechanisms
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Comparative effectiveness of intraarticular injection of PRP and implantation of heparin-conjugated fibrin hydrogel in osteoarthrosis of the knee joint — Mukhtar Abilmazhinov, Arman Batpen, et al. · Medicine and ecology (2025) | TGRS Research Map | TGRS