Comparative effectiveness of intraarticular injection of PRP and implantation of heparin-conjugated fibrin hydrogel in osteoarthrosis of the knee joint
Aim of the study . The article is devoted to the current trend of modern orthopedics – the surgical treatment of local full-thickness defects in the hyaline cartilage of the knee joint. This pathology is diagnosed in 5-10% of patients with diseases and injuries of the knee joint. Materials and methods . The authors of the article presented one of the most modern and available technologies for the restoration of cartilage defects – the implantation of Heparin-Conjugated Fibrin Hydrogel. This operation technique was used in 38 patients. The article presents the indications and technique of surgery, criteria for evaluating treatment outcomes. Results and discussion . Treatment outcomes in terms of up to 2 years were studied in 38 patients. Good treatment results were observed in 33 patients. In all cases, high-quality and regeneration of the cartilaginous surface of the femoral condyles was achieved. Conclusion . Analysis of the outcomes of treatment of patients after implantation implantation of Heparin- Conjugated Fibrin Hydrogel allows the authors of the article to recommend this technique for widespread use in clinical practice.
Authors
- Mukhtar Abilmazhinov (ORCID: https://orcid.org/0000-0002-8688-6329)
- Arman Batpen (ORCID: https://orcid.org/0000-0002-6661-8132)
- Tusipkhan Toktarov
- Dina Saginova (ORCID: https://orcid.org/0000-0001-9551-5354)
- Bagdat Balbossynov
- Vyacheslav B. Ogay (ORCID: https://orcid.org/0000-0001-5029-5255)
- Yerik Raimagambetov (ORCID: https://orcid.org/0009-0007-9856-7724)
- Kaissar Karkyn
Institutions
- Central Scientific Research Institute of Traumatology and Orthopedics (RU)
- Astana Medical University (KZ)
- Alikhan Bokeikhan University
Publication Details
- Journal
- Medicine and ecology
- Published
- 2025-01-22
- DOI
- https://doi.org/10.59598/me-2305-6045-2024-113-4-91-102
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00