COMPLEX MEASURES TO RESTORE REPRODUCTIVE FUNCTION IN WOMEN WITH POST-COVID-19

Objective. To determine the effectiveness of a complex of measures to restore reproductive function in women with post-COVID-19. Materials and methods. Recommended treatments include balanced nutrition, psychotherapy and psychocorrection, necessary hormone therapy, immunomodulators, means to improve folate metabolism, reduce homocysteine and melatonin metabolism, eliminate vitamin D deficiency, drugs with antioxidant and anti-inflammatory properties, and those that positively affect the vascular endothelium. One hundred patients with infertility and longCOVID-19 were examined: the main group - 50 women who used the recommended complex before ART programs and the comparison group - 50 women who did not use additional training. Results. As a result of the application of the recommended complex of therapeutic and preventive measures for women with infertility and long-COVID-19, the following was achieved: a decrease in the manifestations of SVD, clinical anxiety, and depression, balancing of the hormonal background and improvement of the condition of the vessels, which in the complex allowed to reduce the manifestations of long-COVID-19 significantly. The main result of the application of the recommended complex is an increase in the effectiveness of ART programs: the frequency of clinical pregnancy increased to 36.0 versus 20.0% (p < 0.05), and live birth was recorded in 36.0% versus 16.0% (p < 0.05). Conclusion. The high effectiveness of the proposed therapeutic and preventive complex for increasing the effectiveness of ART programs in women with long-COVID-19 allows us to recommend it for widespread use in human reproduction centers.