Targeting the Neuro-vascular Presynaptic Signalling in STROKE: Evidence and Therapeutic Implications
Our findings identify the changes in presynaptic gene regulation in micro-vessels following ischaemic stroke. Targeting presynaptic active zone protein signalling could represent a promising therapeutic target in mitigating ischaemic stroke.
Authors
- Roxane Isabelle Kestner
- Shimantika Maikap (ORCID: https://orcid.org/0000-0002-9606-2884)
- Alexandra Lucaciu (ORCID: https://orcid.org/0000-0001-5783-088X)
- Rajkumar Vutukuri (ORCID: https://orcid.org/0000-0002-7890-9471)
- Apu Chakraborty
- Anil Annamneedi (ORCID: https://orcid.org/0000-0002-6743-8627)
Institutions
- Goethe University Frankfurt (DE)
- SRM Institute of Science and Technology (IN)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Annals of Neurosciences
- Published
- 2025-01-28
- DOI
- https://doi.org/10.1177/09727531241310048
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- SRM Institute of Science and Technology