An Aligned-to-Random PLGA/Col1-PLGA/nHA Bilayer Electrospun Nanofiber Membrane Enhances Tendon-to-Bone Healing in a Murine Model
This study introduces a biomimetic nanofiber membrane enhancing tendon-to-bone healing, which is crucial for sports medicine. Its efficacy in improving healing outcomes, including bone and cartilage formation and biomechanical strength, could significantly lower failure rates in surgical procedures such as rotator cuff repair and anterior cruciate ligament reconstruction. This advancement offers promising implications for patient recovery and the effectiveness of surgical interventions in tendon-to-bone injuries.
Authors
- Kanglai Tang (ORCID: https://orcid.org/0000-0002-0370-106X)
- Baoyun Xu (ORCID: https://orcid.org/0000-0001-6479-8347)
- Gang He (ORCID: https://orcid.org/0000-0001-9806-4069)
- Mei Zhou (ORCID: https://orcid.org/0000-0002-6481-2206)
- Lin Guo (ORCID: https://orcid.org/0000-0003-4718-6706)
- Shang Gao (ORCID: https://orcid.org/0000-0002-8659-9426)
- Wan Chen (ORCID: https://orcid.org/0000-0001-5734-3432)
- Tao Xu (ORCID: https://orcid.org/0000-0002-6897-5993)
- Yunjiao Wang (ORCID: https://orcid.org/0000-0003-1108-7079)
- Yuzhen Tang
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- The American Journal of Sports Medicine
- Published
- 2025-01-28
- DOI
- https://doi.org/10.1177/03635465241310530
- Citations
- 11
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 18.93
Funders
- National Natural Science Foundation of China
- Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission