A reagent to access methyl sulfones
A chemical reagent to access methyl sulfones has been developed. Its reaction with various bis-nucleophiles leads to the rapid formation of previously unknown heteroaromatic methyl sulfones. Analogous strategy can also be used to construct alkyl-, CHF<sub>2</sub>-, CF<sub>3</sub>- and even bicyclo[1.1.1]pentane-containing derivatives. These compounds have been demonstrated to have a high potential for use in medicinal chemistry and coordination chemistry.
Authors
- H. V. Rasika Dias (ORCID: https://orcid.org/0000-0002-2362-1331)
- Iryna V. Sadkova
- Pavel K. Mykhailiuk (ORCID: https://orcid.org/0000-0003-1821-9011)
- Yurii V. Dmitriv
- Vasyl Ripenko (ORCID: https://orcid.org/0000-0002-9542-9023)
- Angelina V. Biitseva
- Iryna Pishel (ORCID: https://orcid.org/0000-0002-5267-6817)
- Vo Quang Huy Phan (ORCID: https://orcid.org/0009-0004-3436-4168)
- Sergei Bova
- Andrei A. Tolmachev
- Yaroslav Poplavskyi
- Oleksii Grygorov
Institutions
- The University of Texas at Arlington (US)
- Taras Shevchenko National University of Kyiv (UA)
- National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute” (UA)
- Enamine (Ukraine) (UA)
Publication Details
- Journal
- Nature Communications
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1038/s41467-024-55027-x
- Citations
- 9
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 8.42