Effects of Psilocybin on Mouse Brain Microstructure

Diffusion microstructure imaging and white matter tractography are sensitive methods to detect and characterize the neural substrates and microstructural differences accompanying psilocybin treatment. These findings suggest the potential role for diffusion microstructure imaging to quantify the bioeffects of psychedelics like psilocybin on the brain, monitor treatment response, and identify salient clinical end points in an emerging therapeutic option for patients with MDD.

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Publication Details

Journal
American Journal of Neuroradiology
Published
2025-01-29
DOI
https://doi.org/10.3174/ajnr.a8634
Citations
1
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
2.31
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article

Effects of Psilocybin on Mouse Brain Microstructure

John‐Paul J. Yu, Matthew I. Banks, Nicholas A. Stowe, Ajay Paul Singh et al.
1 citations
American Journal of Neuroradiology
Psychedelics and Drug Studies
2.31
article

Effects of Psilocybin on Mouse Brain Microstructure

John‐Paul J. Yu, Matthew I. Banks, Nicholas A. Stowe, Ajay Paul Singh, Zarmeen Zahid, Sean M. Grady, Paloma C. Frautschi
article en
1 citations

Abstract

Diffusion microstructure imaging and white matter tractography are sensitive methods to detect and characterize the neural substrates and microstructural differences accompanying psilocybin treatment. These findings suggest the potential role for diffusion microstructure imaging to quantify the bioeffects of psychedelics like psilocybin on the brain, monitor treatment response, and identify salient clinical end points in an emerging therapeutic option for patients with MDD.

American Journal of NeuroradiologyVol. 46(6)
University of Wisconsin–Madison (US), Zimmer Biomet (Netherlands) (NL), Oncoscience (Germany) (DE), Wisconsin Division of Public Health (US)
Zero hunger
Openalex Percentile: Top 18%
Psychedelics and Drug Studies
2.31
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Effects of Psilocybin on Mouse Brain Microstructure — John‐Paul J. Yu, Matthew I. Banks, et al. · American Journal of Neuroradiology (2025) | TGRS Research Map | TGRS