Wider antibody breadth against multiple Plasmodium falciparum antigens is associated with reduced risk of malaria in a transmission hotspot in southern Ghana
Specific antibody levels and breadth of responses against multiple P. falciparum surface antigens protect against febrile malaria, parasitaemia and multiple malaria episodes. This data supports the development of multivalent vaccines targeting P. falciparum surface antigens in high malaria endemic settings.
Authors
- Daniel Dodoo
- Susheel Kumar Singh (ORCID: https://orcid.org/0000-0002-1489-8742)
- Duah Dwomoh (ORCID: https://orcid.org/0000-0002-2726-9929)
- Quratul-ain Issahaque
- Bright Adu (ORCID: https://orcid.org/0000-0002-3622-2137)
- Michael Theisen (ORCID: https://orcid.org/0000-0003-4412-1392)
- Eric Kyei‐Baafour (ORCID: https://orcid.org/0000-0001-6423-1885)
- Eunice Owusu-Yeboa
- Selassie Kumordjie
- Kwadwo Asamoah Kusi (ORCID: https://orcid.org/0000-0001-5483-9985)
- Fareed K N Authur
Institutions
- Statens Serum Institut (DK)
- University of Ghana (GH)
- Kwame Nkrumah University of Science and Technology (GH)
- Noguchi Memorial Institute for Medical Research (GH)
- Regional Medical Research Centre (IN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1016/j.ijid.2025.107804
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Communities, Government of Western Australia
- Danida Fellowship Centre
- Udenrigsministeriet