Systematic Review of the Effects of Iron on Cardiovascular, Kidney, and Safety Outcomes in Patients With CKD
Iron therapy may reduce the risk of heart failure and cardiovascular death in patients with CKD. Randomized trials evaluating the effects of iron on clinical outcomes are needed, especially in nondialysis patients with CKD with or without anemia.
Authors
- Bernard Chan (ORCID: https://orcid.org/0000-0002-9541-7575)
- Brendon Lange Neuen (ORCID: https://orcid.org/0000-0001-9276-8380)
- Murilo Guedes (ORCID: https://orcid.org/0000-0002-3495-852X)
- Vlado Perkovic (ORCID: https://orcid.org/0000-0002-4257-7620)
- Glenn M. Chertow (ORCID: https://orcid.org/0000-0002-7599-0534)
- Amanda Varghese
- Roberto Pecoits‐Filho (ORCID: https://orcid.org/0000-0002-0255-6710)
- Rebecca Kozor (ORCID: https://orcid.org/0000-0002-6437-5018)
- Clare Arnott (ORCID: https://orcid.org/0000-0001-9370-9913)
- Muthiah Vaduganathan (ORCID: https://orcid.org/0000-0003-0885-1953)
- Geoffrey A. Block (ORCID: https://orcid.org/0000-0002-4646-7074)
- Sunil V. Badve (ORCID: https://orcid.org/0000-0003-2269-312X)
- Sradha S. Kotwal (ORCID: https://orcid.org/0000-0002-3294-4087)
- Min Jun (ORCID: https://orcid.org/0000-0003-1460-7535)
- Emma O’Lone
- Scott D Solomon
Institutions
- Brigham and Women's Hospital (US)
- The University of Sydney (AU)
- Harvard University (US)
- Royal Prince Alfred Hospital (AU)
- Royal North Shore Hospital (AU)
- Renal Association (GB)
- UNSW Sydney (AU)
- Prince of Wales Hospital (AU)
- The George Institute for Global Health (AU)
- St George Hospital (AU)
- Arbor Research Collaborative for Health (US)
- Stanford University (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1016/j.ekir.2025.01.029
- Citations
- 6
- Primary Topic
- Erythropoietin and Anemia Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.62
Funders
- Amgen
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Bayer
- GlaxoSmithKline
- Sanofi
- Gilead Sciences
- Alexion Pharmaceuticals
- Alnylam Pharmaceuticals
- CSL Behring
- Celladon Corporation
- Ramaciotti Foundations
- Cytokinetics
- Sarepta Therapeutics
- ReCor Medical
- Fresenius Medical Care North America
- MyoKardia
- Impulse Dynamics
- Moderna
- Satellite Healthcare
- Bayer HealthCare
- Daiichi-Sankyo
- Novo Nordisk
- Vifor Pharma
- Otsuka Pharmaceutical
- Akebia Therapeutics
- National Institutes of Health
- Sanofi Pasteur
- American Regent
- Respicardia
- Medical Research Council
- National Health and Medical Research Council
- Relypsa
- National Heart, Lung, and Blood Institute