Association of physical metabolic markers with perinatal outcomes in low-risk pregnant women: a prospective cohort study

Background: This prospective study was planned to study the correlation of all physical metabolic markers (BMI, WC, WHR, and WHtR) in the antenatal period with perinatal outcomes. Methods: All pregnant women who had first antenatal visit before 20 weeks were recruited into the study for period of 1 year. Detailed history was taken followed by a thorough general physical examination (including BMI, WC, WHR, and WHtR as per Indian standards). Results: In multivariate logistic regression model none of parameters actually predicted the onset of GDM. Incidence of LSCS showed significant association with WC and WHtR. BW>3.5 kgs and NICU admission had a significant statistical association with WHtR. Conclusions: BMI, WC, WHR and WHtR should be measured in all pregnant women at the first antenatal visit. WC predicts caesarean delivery, BMI predicts large for gestational age baby, and WHtR is a novel marker which predicts both.