Adverse Reactions to Cosmetic Fillers in the Oral and Maxillofacial Region: Clinico‐Pathological, Histochemical, and Immunohistochemical Characterization
An evident macrophage reaction is observed in all aesthetic fillers, frequently associated with giant cell formation. Despite similarities, there are specific features of each material and the host response that assist the correct histopathological diagnosis. Immunohistochemistry for CD68 and Toluidine blue stain are useful in doubtful cases.
Authors
- Ana Paula Neutzling Gomes (ORCID: https://orcid.org/0000-0003-2214-5246)
- Ana Carolina Uchôa Vasconcelos (ORCID: https://orcid.org/0000-0001-6560-9536)
- Lucas Guimarães Abreu (ORCID: https://orcid.org/0000-0003-2258-8071)
- Ricardo Alves Mesquita (ORCID: https://orcid.org/0000-0003-3207-4007)
- Diego Antônio Costa Arantes (ORCID: https://orcid.org/0000-0002-1306-747X)
- Sílvia Ferreira de Sousa (ORCID: https://orcid.org/0000-0001-7820-4749)
- Tarcı́lia Aparecida Silva (ORCID: https://orcid.org/0000-0001-9623-7835)
- Cassiano Francisco Weege Nonaka (ORCID: https://orcid.org/0000-0003-2380-109X)
- Pollianna Muniz Alves (ORCID: https://orcid.org/0000-0003-1297-4032)
- Elismauro Francisco Mendonça (ORCID: https://orcid.org/0000-0002-6751-3279)
- Ana Cristina Tetzner (ORCID: https://orcid.org/0000-0002-5281-3690)
- Patrícia Carlos Caldeira (ORCID: https://orcid.org/0000-0002-9179-0145)
- Roberto Onner Cruz Tapia
- Laura Regina Mendes Viana
Institutions
- Universidade Federal de Minas Gerais (BR)
- Universidade Estadual da Paraíba (BR)
- Universidade Federal de Pelotas (BR)
- Universidade Federal de Goiás (BR)
- Technological University of Mexico (MX)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1111/jop.13604
- Citations
- 4
- Primary Topic
- Facial Rejuvenation and Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 8.02
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Pró-Reitoria de Pesquisa, Universidade Federal de Minas Gerais