Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated C. acnes-treated SZ95 sebocytes
This study's findings indicate that PM potentially aggravates acne by acting on both inflammation and sebum secretion. They also reveal afzelin's ability to suppress these phenomena by not only suppressing inflammatory cytokine expression but also inhibiting sebogenesis. These findings confirm afzelin's potential therapeutic role in improving PM-exacerbated acne.
Authors
- Christos C. Zouboulis (ORCID: https://orcid.org/0000-0003-1646-2608)
- Kui Young Park (ORCID: https://orcid.org/0000-0001-5965-1754)
- Ji Yeon Hong (ORCID: https://orcid.org/0000-0002-5632-8449)
- Yoon Jin Roh
- Mi‐Kyung Lee (ORCID: https://orcid.org/0000-0002-6064-5295)
- Yong Hee Choi
Institutions
- Städtisches Klinikum Dessau (DE)
- Chung-Ang University Hospital (KR)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fmed.2025.1518382
- Citations
- 3
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 4.87
Funders
- Chung-Ang University
- Korea Health Industry Development Institute