Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study
Jiawei Suanzaoren Decoction can improve the perimenopausal insomnia. The mechanism behind this improvement may be related to the regulation of Estradiol (E2), Follicle-Stimulating Hormone (FSH), and luteinizing hormone (LH) levels, as well as the mRNA expression levels of 5-HT<sub>1a</sub>, 5-HT<sub>2a</sub>, GABAAR<sub>α1</sub>, and GABAAR<sub>γ2</sub> receptors in the hypothalamus.
Authors
- Chen Li-qiong (ORCID: https://orcid.org/0000-0002-1238-860X)
- Ning Fang (ORCID: https://orcid.org/0000-0001-7000-0207)
- Mingjin Zhu (ORCID: https://orcid.org/0000-0003-4589-2287)
- Yongcan Zhou
Institutions
- Tongde Hospital of Zhejiang Province (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fphar.2024.1495957
- Citations
- 4
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 8.47
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province