Proximal bronchiolar adenoma with malignant transformation to invasive mucinous adenocarcinoma with 4 years follow-up: a case report and literature review
In this case, the detection of driver gene <i>KRAS</i> mutation and loss of continuity in the basal cell layer within the mucous glandular structures of the nodule suggests the malignant transformation of BA into IMA, inferring the malignant potential of BA.
Authors
- Xinzhi Feng
- Ke Yin
- Xiaoying Xu (ORCID: https://orcid.org/0000-0001-8914-5262)
- Yongqiang Yang (ORCID: https://orcid.org/0000-0002-6981-4833)
- Jiaqi Xu
- Jixuan Liu (ORCID: https://orcid.org/0000-0001-9703-9224)
- Junlei Zhang (ORCID: https://orcid.org/0000-0003-3344-759X)
- Xiaoyan Lin
Institutions
- Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fonc.2025.1491339
- Citations
- 1
- Primary Topic
- Medical Imaging and Pathology Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.52