Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head
Serum and local GRP78 as well as CHOP expressions were positively linked with disease progression in NT-ONFH patients. Potential therapeutics targeting ER stress related protein may serve as a method for alleviating NT-ONFH.
Authors
- Qing-He Ye
- Biao-Fang Wei (ORCID: https://orcid.org/0009-0002-1035-4403)
- Yongheng Zhao (ORCID: https://orcid.org/0000-0001-5298-2833)
- Zhu Hong-xun
- Peng Zhang (ORCID: https://orcid.org/0000-0001-5574-0899)
- Wenxiu Zhu (ORCID: https://orcid.org/0000-0002-5993-3302)
Institutions
- Guangzhou University (CN)
- Linyi People's Hospital (CN)
- Linyi City Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1186/s13018-025-05541-5
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.72