Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping
This study contributes to the understanding of immune dynamics in chronic liver disease among different etiologies. B lymphocytes are relatively reduced in alcohol-related liver disease compared to other groups, and T cells exhibit a more differentiated subtype. The peritumor microenvironment in HCC suggests a relatively diminished presence of NK cells and a potential tendency toward increased inhibitory characteristics.
Authors
- Özgür Albayrak (ORCID: https://orcid.org/0000-0001-8760-1439)
- Murat Dayangaç (ORCID: https://orcid.org/0000-0002-1240-7233)
- Bürge Ulukan (ORCID: https://orcid.org/0000-0002-1101-8834)
- Murat Akyıldız (ORCID: https://orcid.org/0000-0002-2080-7528)
- Atay Vural (ORCID: https://orcid.org/0000-0003-3222-874X)
- Adil Mardinoğlu (ORCID: https://orcid.org/0000-0002-4254-6090)
- Buket Yiğit
- Sina Soleimani (ORCID: https://orcid.org/0000-0002-3914-2909)
- Kayra Somay (ORCID: https://orcid.org/0000-0001-5089-4653)
- Dila Atak (ORCID: https://orcid.org/0000-0001-8882-0019)
- Hong Yang (ORCID: https://orcid.org/0000-0001-7126-3076)
- Elif Demirtaş (ORCID: https://orcid.org/0000-0002-6024-8038)
- M Gürsoy (ORCID: https://orcid.org/0000-0002-8189-6501)
- Müjdat Zeybel (ORCID: https://orcid.org/0000-0001-5440-4623)
Institutions
- Koç University (TR)
- King's College London (GB)
- Science for Life Laboratory (SE)
- Istanbul Medipol University (TR)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fmolb.2024.1521811
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00