Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer

Carboplatin resistance-related DDR genes are associated with prognosis, immune infiltration, and drug sensitivity in breast cancer patients. TONSL may serve as a potential therapeutic target for breast cancer, particularly in triple-negative breast cancer, indicating new treatment strategies for these patients.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-01-29
DOI
https://doi.org/10.3389/fimmu.2025.1522149
Citations
1
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
1.05

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article

Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer

Ruijun Pan, Shuwen Dong, Kunwei Shen, Zheng Wang et al.
1 citations
Frontiers in Immunology
Cancer Immunotherapy and Biomarkers
1.05
article

Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer

Ruijun Pan, Shuwen Dong, Kunwei Shen, Zheng Wang, Anqi Li, Jin Hong
article en
1 citations

Abstract

Carboplatin resistance-related DDR genes are associated with prognosis, immune infiltration, and drug sensitivity in breast cancer patients. TONSL may serve as a potential therapeutic target for breast cancer, particularly in triple-negative breast cancer, indicating new treatment strategies for these patients.

Frontiers in ImmunologyVol. 16
Shanghai Jiao Tong University (CN), Ruijin Hospital (CN)
Shanghai Municipal Health Commission, National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 26%
Cancer Immunotherapy and Biomarkers
1.05
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