Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis
This study provides a comprehensive transcriptomic overview of IPF, uncovering DEGs, hub proteins, and regulatory signatures implicated in disease progression. Validation in independent datasets confirmed the relevance of these findings. The insights gained here lay the groundwork for developing diagnostic tools and novel therapeutic strategies for IPF.
Authors
- Mohammad Jakir Hosen (ORCID: https://orcid.org/0000-0001-6444-0214)
- Abdullah Al Emran (ORCID: https://orcid.org/0000-0001-5518-6605)
- M. Elahi (ORCID: https://orcid.org/0000-0001-8148-3347)
- Sambit Das
- Arnab Halder (ORCID: https://orcid.org/0000-0003-3606-3532)
- Abu Tayab Moin (ORCID: https://orcid.org/0000-0002-2954-3215)
- Tawsif Al Arian
- Jannatul Ferdous Nipa
- Md. Minhazul Islam
- M. S. Rahman (ORCID: https://orcid.org/0000-0002-5960-0161)
- Umme Sadea Rahman (ORCID: https://orcid.org/0009-0001-2248-2798)
- Mitu Akter (ORCID: https://orcid.org/0009-0002-6955-6157)
- Md. Asad Ullah
- Shoaib Saikat
Institutions
- Shahjalal University of Science and Technology (BD)
- University of Barishal (BD)
- BGC Trust University Bangladesh (BD)
- Independent University, Bangladesh (BD)
- Anhalt University of Applied Sciences (DE)
- University of Asia Pacific (BD)
- Jahangirnagar University (BD)
- East West University (BD)
- University of Chittagong (BD)
- University of Science and Technology Chittagong (BD)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fgene.2024.1496462
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00