Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep
TAAR2-9 modulates sleep/wake states and interacts with TAAR1. These findings highlight the therapeutic potential of targeting TAARs 2-9 in sleep-related neuropsychiatric disorders. Further research is needed to elucidate their roles.
Authors
- Meghan Haire (ORCID: https://orcid.org/0000-0002-8405-4692)
- Shun‐Chieh Ma (ORCID: https://orcid.org/0000-0002-5222-778X)
- Jasmine Heu (ORCID: https://orcid.org/0000-0002-4357-2573)
- Yu Sun (ORCID: https://orcid.org/0000-0001-5002-1414)
- Marius C. Hoener (ORCID: https://orcid.org/0000-0001-6510-6250)
- Ryan K. Tisdale (ORCID: https://orcid.org/0000-0002-8239-6576)
- Thomas S. Kilduff (ORCID: https://orcid.org/0000-0002-6823-0094)
- Sunmee Park (ORCID: https://orcid.org/0000-0001-6047-0774)
- Gavin Scheldrup
Institutions
- Roche (Switzerland) (CH)
- SRI International (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fpsyt.2024.1467964
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Neurological Disorders and Stroke