Exploring the association between herbal medicine usage and drug-induced liver injury: insights from a nationwide population-based cohort study using SCCS in South Korea
This nationwide cohort study demonstrates that herbal medicines prescribed by TKM practitioners have minimal impact on DILI risk. Patients with pre-existing liver disease exhibit increased susceptibility to DILI. Differentiating between unregulated herbal products and those prescribed in medical institutions is essential for accurate assessment of hepatotoxicity risk.
Authors
- Sungho Won (ORCID: https://orcid.org/0000-0001-5751-5089)
- Sanghun Lee (ORCID: https://orcid.org/0000-0002-0573-9555)
- Tae‐Hyun Yang (ORCID: https://orcid.org/0000-0003-1594-3696)
- Juhee Ahn (ORCID: https://orcid.org/0000-0002-4487-7707)
Institutions
- Seoul National University (KR)
- Dankook University (KR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fphar.2025.1498124
- Citations
- 1
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Korea Health Industry Development Institute