The gut microbiota regulates diabetic retinopathy in adult rats
Our data suggests that ABX gavage-induced gut dysbiosis can reduce retinal microglia in adult rats and alleviate RGC loss in long-term T2D rats. Targeting the gut microbiota may be a future therapeutic strategy for DR management.
Authors
- Zhongping Lv
- Jueyu Hou
- Danian Chen (ORCID: https://orcid.org/0000-0002-6916-2978)
- Yujiao Wang (ORCID: https://orcid.org/0000-0001-6860-1310)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fmicb.2025.1479792
- Citations
- 6
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.05
Funders
- National Natural Science Foundation of China