Lavado con HCG previo a transferencia embrionaria en una clínica de reproducción humana asistida, ubicada sobre 2800 msnm, en Ecuador

This study analyzed the effect of intrauterine hCG washout prior to embryo transfer in 17 patients in an assisted reproduction clinic in Latacunga, Ecuador, located at 2800 masl. A dose of 500 IU of hCG administered 15 minutes before transfer was used. The primary outcomes evaluated were the clinical pregnancy rate (positive quantitative B-hCG and positive embryonic heartbeat), obtaining a rate of 18%. Among the secondary outcomes, it was noted that most patients used their own eggs and sperm (41%), and a single embryo was transferred in 53% of the cases. The main cause of infertility was idiopathic (41%). Although the use of intrauterine hCG showed potential benefits in previous studies for cases with recurrent implantation failure, no significant improvement in reproductive outcomes was evident in this context. This highlights the complexity of the molecular and cellular processes involved in embryo implantation. It is suggested that the technique may be useful in specific cases of previous implantation failure, but further studies are required to evaluate its effectiveness under heterogeneous conditions.