The impact of SLCO1B1 polymorphisms on homocysteine concentrations: evidence for a stronger association in men
Folic acid and vitamin B12 reduce Hcy concentrations, while the SLCO1B1 CT and CC polymorphisms are associated with higher Hcy levels. The impact of SLCO1B1 gene polymorphism on Hcy is notably stronger in the male population, suggesting that genetic factors play a significant role in determining Hcy levels.
Authors
- Yonghua Jiang
- Xinyuan Hu (ORCID: https://orcid.org/0000-0002-7443-1474)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Nephrology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.3389/fneph.2024.1465380
- Citations
- 2
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- National Natural Science Foundation of China
- People's Government of Jilin Province