Integration of apolipoprotein B into the SCORE2 framework: implications for cardiovascular risk prediction
Apolipoprotein B exhibited a dose-response relationship with cardiovascular risk but had limited standalone predictive utility within the UK Biobank population. However, combining ApoB with SCORE2 thresholds improved the identification of low-risk individuals, suggesting a complementary role for ApoB in refining cardiovascular risk stratification.
Authors
- Lê Thị Phương Thảo (ORCID: https://orcid.org/0000-0001-9661-6835)
- Derek P. Chew (ORCID: https://orcid.org/0000-0003-3593-296X)
- Karlheinz Peter (ORCID: https://orcid.org/0000-0002-8040-2258)
- Wen Kai Wong (ORCID: https://orcid.org/0000-0003-1712-0984)
- Stephen James Nicholls (ORCID: https://orcid.org/0000-0002-9668-4368)
- Fumihiko Takeuchi (ORCID: https://orcid.org/0000-0003-3185-5661)
Institutions
- Baker Heart and Diabetes Institute (AU)
- The University of Melbourne (AU)
- Monash Health (AU)
- Melbourne Health (AU)
- Imperial College London (GB)
- Monash University (AU)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1093/eurjpc/zwaf039
- Citations
- 2
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 4.01