A quality-by-design approach to develop abemaciclib solid lipid nanoparticles for targeting breast cancer cell lines
The use of QbD to achieve high entrapment efficiency and sustained release in ABE-SLNs, coupled with enhanced cellular uptake and cytotoxicity, represents a novel approach that could set a new standard for nanoparticle-based drug delivery systems.
Authors
- Wei Meng Lim
- Samah Hamed Almurisi (ORCID: https://orcid.org/0000-0002-6435-9640)
- Thiagarajan Madheswaran (ORCID: https://orcid.org/0000-0001-5049-0659)
- Barry L. Chin
Institutions
- Australian Regenerative Medicine Institute (AU)
- Indian Maritime University (IN)
- Monash University (AU)
- IMU University (MY)
Publication Details
- Journal
- Therapeutic Delivery
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1080/20415990.2025.2457314
- Citations
- 4
- Primary Topic
- Advanced Breast Cancer Therapies
- Type
- article
- Field-Weighted Citation Impact
- 6.07