Identification of near full-length human pegivirus type 2 (HPgV-2) genomes in blood donor samples co-infected with hepatitis C virus (HCV)
Human pegivirus (HPgV) identified from an HCV-infected plasma sample through nanopore metagenomics. The analysis revealed a nearly complete HPgV-2 genome. Phylogenetic analysis confirmed its classification within the HPgV-2 genotype, providing insights into viral co-infection dynamics. The metagenomics approach advances the understanding of viral diversity and supports the development of accurate diagnostics.
Authors
- Kylan Kelley (ORCID: https://orcid.org/0009-0008-2188-5166)
- Viswanath Ragupathy (ORCID: https://orcid.org/0000-0003-2509-2805)
- Indira Hewlett (ORCID: https://orcid.org/0000-0002-2951-7885)
Institutions
- Center for Biologics Evaluation and Research (US)
- Food and Drug Administration (TH)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1128/mra.01179-24
- Citations
- 1
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 1.32