λ-cyhalothrin induced sex-specific inflammation, glia activation and GABAergic interneuron disruption in the hippocampus of rats

LCT specifically induced inflammation and disrupted GABAergic interneurons' integrities via activation of microglia and reactive astrogliosis and such effects are dose-dependent and sexually dimorphic.

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Publication Details

Journal
BMC Pharmacology and Toxicology
Published
2025-01-29
DOI
https://doi.org/10.1186/s40360-025-00860-z
Citations
3
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
2.53
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article

λ-cyhalothrin induced sex-specific inflammation, glia activation and GABAergic interneuron disruption in the hippocampus of rats

Musa Iyiola Ajibola, Ajala Taofeeqoh Odunayo, Luqman Abu-Bakar, Omamuyovwi M. Ijomone et al.
3 citations
BMC Pharmacology and Toxicology
Neuroinflammation and Neurodegeneration Mechanisms
2.53
article

λ-cyhalothrin induced sex-specific inflammation, glia activation and GABAergic interneuron disruption in the hippocampus of rats

Musa Iyiola Ajibola, Ajala Taofeeqoh Odunayo, Luqman Abu-Bakar, Omamuyovwi M. Ijomone, Christianah Oyegbola, Aminu Imam, Moyosore Salihu Ajao, Wahab Abdulmajeed Imam, Maryam Busari, Aalimah Akinosho Akorede, Adewumi Mercy Gbemisola, Alhassan Godwin Attai
article en
3 citations

Abstract

LCT specifically induced inflammation and disrupted GABAergic interneurons' integrities via activation of microglia and reactive astrogliosis and such effects are dose-dependent and sexually dimorphic.

BMC Pharmacology and ToxicologyVol. 26(1)
University of Maryland, Baltimore (US), University of Ilorin (NG), Illinois State University (US), Olusegun Agagu University of Science and Technology (NG)
Openalex Percentile: Top 12%
Neuroinflammation and Neurodegeneration Mechanisms
2.53
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λ-cyhalothrin induced sex-specific inflammation, glia activation and GABAergic interneuron disruption in the hippocampus of rats — Musa Iyiola Ajibola, Ajala Taofeeqoh Odunayo, et al. · BMC Pharmacology and Toxicology (2025) | TGRS Research Map | TGRS