Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease

The heart H/M ratio and cardiac WR in <sup>123</sup>I-MIBG scintigraphy show high diagnostic efficacy for both diagnosing and differentiating PD. Including cardiac WR in routine assessments is recommended. The diagnostic potential of WR in the parotid and thyroid glands also holds promise for PD diagnosis. Incorporating these parameters could enhance the accuracy of PD diagnosis, particularly in clinical scenarios where concurrent cardiac disease may confound the diagnosis.

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Publication Details

Journal
EJNMMI Research
Published
2025-01-29
DOI
https://doi.org/10.1186/s13550-025-01197-8
Citations
3
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
4.17

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article

Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease

Guanyun Wang, Jigang Yang, Ying Kan, Teng Xue et al.
3 citations
EJNMMI Research
Parkinson's Disease Mechanisms and Treatments
4.17
article

Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease

Guanyun Wang, Jigang Yang, Ying Kan, Teng Xue, Ying Cui
article en
3 citations

Abstract

The heart H/M ratio and cardiac WR in <sup>123</sup>I-MIBG scintigraphy show high diagnostic efficacy for both diagnosing and differentiating PD. Including cardiac WR in routine assessments is recommended. The diagnostic potential of WR in the parotid and thyroid glands also holds promise for PD diagnosis. Incorporating these parameters could enhance the accuracy of PD diagnosis, particularly in clinical scenarios where concurrent cardiac disease may confound the diagnosis.

EJNMMI ResearchVol. 15(1)
Capital Medical University (CN), Beijing Friendship Hospital (CN)
Capital Medical University, Beijing Friendship Hospital, Capital Medical University
Openalex Percentile: Top 8%
Parkinson's Disease Mechanisms and Treatments
4.17
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Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease — Guanyun Wang, Jigang Yang, et al. · EJNMMI Research (2025) | TGRS Research Map | TGRS