Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis

Measurement of CNAs in LGD is an accurate predictor of AN risk in inflammatory bowel disease and is likely to support clinical management.

Authors

Heather E. Grant (ORCID: https://orcid.org/0000-0001-9500-1644)
Qingli Guo (ORCID: https://orcid.org/0000-0001-8467-8828)
Manuel Rodriguez‐Justo (ORCID: https://orcid.org/0000-0001-5007-1761)
Salpie Nowinski (ORCID: https://orcid.org/0000-0001-5686-3778)
Trevor A. Graham (ORCID: https://orcid.org/0000-0001-9582-1597)
Ailsa Hart (ORCID: https://orcid.org/0000-0002-7141-6076)
Ibrahim Al Bakir (ORCID: https://orcid.org/0000-0001-8775-3459)
Ann‐Marie Baker (ORCID: https://orcid.org/0000-0001-8905-9137)
Kane Smith (ORCID: https://orcid.org/0000-0002-8661-7401)
Jennifer Fisher
Nadia Nasreddin (ORCID: https://orcid.org/0000-0002-3025-6213)
Hayley L. Belnoue-Davis (ORCID: https://orcid.org/0000-0003-2914-4932)
George D. Cresswell (ORCID: https://orcid.org/0000-0003-3303-068X)
Nicholas A. Wright (ORCID: https://orcid.org/0000-0002-5525-3457)
Philip D. Dunne (ORCID: https://orcid.org/0000-0001-9160-283X)
Maurice B. Loughrey (ORCID: https://orcid.org/0000-0001-8424-1765)
Christopher Kimberley (ORCID: https://orcid.org/0000-0002-9720-4434)
Maximilian Mossner (ORCID: https://orcid.org/0000-0001-9751-3803)
Ally Speight (ORCID: https://orcid.org/0000-0003-3184-9181)
Kit Curtius (ORCID: https://orcid.org/0000-0002-2678-0960)
Simon J. Leedham (ORCID: https://orcid.org/0000-0003-1476-6982)
Marnix Jansen (ORCID: https://orcid.org/0000-0003-0645-564X)
Morgan Moorghen (ORCID: https://orcid.org/0000-0003-0262-2674)
James E. East (ORCID: https://orcid.org/0000-0001-8035-3700)
Theo Clarke