The Association Between Vitamin D Status With Inflammatory Markers and Clinical Features in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease
This cross-sectional study assessed the association of vitamin D status with inflammatory markers and clinical features in 122 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) who attended the polyclinics in Tabriz, Iran. The diagnosis of MASLD among participants was ultrasonography. The mean serum levels of interleukin-6 (P = .028), tumor necrosis factor-α ( P = .036), and alanine aminotransferase (ALT) ( P = .005) were significantly higher in the patients with vitamin D insufficiency than those with vitamin D sufficiency. Vitamin D insufficiency in patients with MASLD was found to be related to higher inflammation and severity of liver steatosis.
Authors
- Abbas Pishdadian (ORCID: https://orcid.org/0000-0002-2968-6515)
- Soudabeh Hamedi−Shahraki (ORCID: https://orcid.org/0000-0003-2270-7421)
- Zahra Zaer-Sabet
- Farshad Amirkhizi (ORCID: https://orcid.org/0000-0003-1477-0260)
Institutions
- Shahed University (IR)
- Saab (Switzerland) (CH)
- Xidian University (CN)
- Jizzakh State Pedagogical University (UZ)
Publication Details
- Journal
- Topics in Clinical Nutrition
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1097/tin.0000000000000400
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00