Evaluation of IRF7 mRNA and its Association with Promoter Methylation in Kashmiri (North-Indian) Patients with Systemic Sclerosis: A Case-Control Study
IRF7 overexpression in PBMCs from SSc patients may be caused by IRF7 promoter demethylation, and this aberrant expression of IRF7 in SSc might provide a link between the prominent IFN signature and the development of SSc.
Authors
- Sakeena Ayub
- Imtiyaz Ahmad Bhat (ORCID: https://orcid.org/0000-0002-0785-045X)
- Muzaffar Bindroo
- Tabasum Shafi
- Fayaz Ahmad Sofi
- Roohi Rasool
- Mushtaq Dangroo
- Zafar A Shah
Institutions
- Sher-i-Kashmir Institute of Medical Sciences (IN)
Publication Details
- Journal
- Mediterranean Journal of Rheumatology
- Published
- 2024-12-01
- DOI
- https://doi.org/10.31138/mjr.040124.eoi
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00