Histopathological Study of the Lesions of Upper Gastrointestinal Tract Endoscopic Biopsy Specimen in Adult Age Group in a Tertiary Care Hospital

Introduction / Background: Upper gastrointestinal endoscopy along with biopsy plays an critical role in the early diagnosis of neoplasms and gives an opportunity for a broad range of treatment options with a potential for possible cure. Aim: To study the various non neoplastic and neoplastic upper gastrointestinal lesions and to corelate their histopathological findings with endoscopic findings along with age and sex distribution of these lesions. Method: This Prospective crosssectional study was carried out in the Department of Pathology of a Tertiary Health Center and a Teaching Institute. Upper gastrointestinal tract endoscopic biopsy of 600 consecutive specimens received in the Department of Pathology were included in the study. Result: The majority of oesophageal lesions diagnosed were squamous cell carcinoma (34.32%). The most common gastro -oesophageal junction lesion found was Barretts's oesophagus (21.62%). The majority of gastric lesions were gastritis (40.11%). The most common duodenal lesion found was duodenitis (56.47%). Conclusion: Upper gastrointestinal endoscopy is relatively less invasive simple, safe and well tolerated procedure, cost effective and provides good diagnostic yield in confirming various upper gastrointestinal lesions.